In 2005, she appeared in the Disney picture Ice Princess, in which she played ice skating coach Tina Harwood of the film's lead character. She portrayed Claire, a paralyzed woman who wants to die, in the West End drama revival of Whose Life Is It Anyway?. In October 2006, she appeared in a West End production of David Mamet's The Cryptogram at the Donmar Warehouse in London. Since late 2005, she has appeared in a number of British television commercials for Tetley Tea. In July 2006, a commercial for Nissan cars, which featured Cattrall as Samantha Jones, was withdrawn from New Zealand television, apparently because of complaints about its innuendo.13] In 2006, she starred alongside Brendan Gleeson in John Boorman's 2006 film The Tiger's Tail, a black comedy that focuses on the impact of the Celtic Tiger economy on Irish people. On ITV, she starred alongside David Haig, Daniel Radcliffe, and Carey Mulligan in My Boy Jack, the story of author Rudyard Kipling's search for his son lost in World War I.
On 16 June 2009, it was announced that Cattrall would receive a star on Canada's Walk of Fame in Toronto. The induction ceremony was held on 12 September 2009.
In November 2009 whilst filming Sex and the City 2 in Marrakech, Cattrall took part in an seminar, 'Being directed' with Director John Boorman as part of the 3rd Edition of the Arts in Marrakech Festival.
On 24 February 2010, Cattrall began a critically acclaimed run in the West End of London at The Vaudeville Theatre as leading lady, Amanda, opposite Matthew Macfadyen, almost twenty years her junior, in a revival of Noel Coward's play Private Lives. She performed until 3 May 2010.
Cattrall will play Cleopatra in a production of Antony and Cleopatra, directed by Janet Suzman, opposite Jeffery Kissoon as Anthony, in Liverpool at the Playhouse in October 2010. Also scheduled for release is her movie Meet Monica Velour, in which Cattrall plays an out-of-shape former adult star.
In 2010, Cattrall was named an Honorary Fellow of Liverpool John Moores University in recognition of her contributions to the dramatic arts.