First she went to Paris, then met Louis B. Mayer in London. After he hired her, at his insistence, she changed her name to Hedy Lamarr, choosing the surname in homage to a beautiful film star of the silent era, Barbara La Marr, who had died in 1926 from a drug overdose.
In Hollywood, she was usually cast as glamorous and seductive. Her American debut was in Algiers (1938). Her many films include Boom Town (1940), White Cargo (1942), and Tortilla Flat (1942), based on the novel by John Steinbeck. White Cargo, one of Lamarr's biggest hits at MGM, contains arguably her most famous film quote, "Tondelayo make tiffin". In 1941, she was cast alongside two other Hollywood beauties, Lana Turner and Judy Garland in the musical extravaganza Ziegfeld Girl.
She made 18 films from 1940 to 1949 even though she had two children during that time (in 1945 and 1947). She left MGM in 1945; Lamarr enjoyed her biggest success as Delilah in Cecil B. DeMille's Samson and Delilah, the highest-grossing film of 1949, with Victor Mature as the Biblical strongman. However, following her comedic turn opposite Bob Hope in My Favorite Spy (1951), her career went into decline. She appeared only sporadically in films after 1950, one of her last roles being that of Joan of Arc in Irwin Allen's critically panned epic The Story of Mankind (1957).